To evaluate the safety and long-term efficacy of fractional CO2 laser treatment in reducing the severity of symptoms of genitourinary syndrome of meno-pause (GSM) in menopausal women.
Growth factors released by platelets have an important role in inflammation reduction, angiogenesis stimulation, and collagen III synthesis. The procedure can be considered effective as therapy for lichen sclerosus disease (3). Future research is needed to elucidate the role of PRP in the treatment of skin conditions like LS.
This question still remains unanswered whether needling with saline can result in the same outcome as PRP due to break down of sclerotic tissue. There is an undeniable need for further Randomized Controlled Trials to compare the outcomes between these two treatment methods.